New Orleans Saints at Philadelphia Eagles

November 21st – 1:00 pm ET – Lincoln Financial Field

The New Orleans Saints have not been the same team since starting quarterback Jameis Winston went down with a torn ACL. He was forced to undergo surgery and will be out of action for quite some time. Since his injury on October 31st, the Saints have lost back-to-back games and could be in trouble in Philadelphia against the Eagles in week 11. They still have hopes of winning their division or making the playoffs, but will need to start picking up wins if they have any chance of doing so.

The Eagles have now won two of their last three games, but are still just 4-6 on the season. They have yet to win a game on home field this year and will be desperate to send the fans home happy on Sunday afternoon.

The Eagles enter the game as minor 1.5-point favorites, in a game that should be quite interesting to keep an eye on. Take the home team and the under in this one. 

PICKS: Philadelphia

ODDS: Philadelphia (-1.5)
Over/Under: 43.5

Pittsburgh Steelers at Los Angeles Chargers 

November 21st – 8:20 pm ET – SoFi Stadium 

The Pittsburgh Steelers are coming off a disappointing tie at home against the winless Detroit Lions, but were without starting quarterback Ben Roethlisberger who tested positive for COVID-19. He is fully vaccinated so could possibly return for Sunday night’s game as long as he isn’t showing symptoms and can provide two negative tests. Even if he is able to return though, it remains to be seen what kind of shape he will be in when he takes the field. If he is unable to play, backup quarterback Mason Rudolph will get the start for the second straight week.

The Los Angeles Chargers are listed as 4.5-point favorites on Sunday night as a result of Roethlisberger’s questionable status and will be hoping to take advantage of the situation. They have dropped two straight home games though and will need to pick up a big win against the Steelers at SoFi Stadium if they would like to keep their playoff hopes alive. This will be an intense battle, regardless of who is in the lineup.

Go with the visitors to keep the game close though and cover the spread.

PICKS: Pittsburgh

ODDS: Los Angeles (-4.5)
Over/Under: 46.5

Indianapolis Colts at Buffalo Bills 

November 21st– 1:00 pm ET – Highmark Stadium

The Buffalo Bills were shocked two weeks ago by the Jacksonville Jaguars and held without a touchdown. Last week though, they put up 45 points against the New York Jets, proving they are still a dominant team. They will be motivated to pick up an important win against an AFC rival on Sunday afternoon, as they look to solidify their spot atop the AFC East. 

The Indianapolis Colts were eliminated in the Wild Card Round last year at Highmark Stadium and will be hoping to get some revenge in week 11. However, they are up against one of the top teams in the conference and will be playing in front of a raucous crowd.  They might be able to keep this game closer than most anticipate, but will be in for a long afternoon in Buffalo.

The Bills enter the contest as seven-point favorites and with good reason. Go with the home team to win and cover the spread in what should be an entertaining contest. The over is also worth laying money on.

PICKS: Buffalo

ODDS: Buffalo (-7)
Over/Under: 48.5

Dallas Cowboys at Kansas City Chiefs    

November 21st – 4:25 pm ET – Arrowhead Stadium 

The Dallas Cowboys head to Kansas City on Sunday afternoon to play the Chiefs in what should be one of the most entertaining and intense games of the week. Both teams will be confident heading into the contest and we should be in for a great battle all afternoon.

The Cowboys are coming off an impressive 43-3 victory over the Atlanta Falcons as they continue to prove themselves as legitimate Super Bowl contenders. They will not be afraid of last year’s Super Bowl finalists and will be ready for what Patrick Mahomes has prepared.

The Chiefs are winners of three straight games though and are finding their momentum at the right time of the campaign. While they struggled to start the season, they have shown what they are capable of in recent weeks and will be eager to pick up a victory over the Cowboys on home field.

The Chiefs are two-point favorites at home, but go with the visitors to cover the spread and potentially win the game outright.

PICKS: Dallas

ODDS: Kansas City (-2)
Over/Under: 55.5

New York Giants at Tampa Bay Buccaneers      

November 22nd – 8:15 pm ET – Raymond James Stadium

The defending Super Bowl champions are coming off a disappointing loss away to Washington Football Club. They have now dropped consecutive contests and will be desperate to pick up the victory in front of their home fans on Monday night. They should have no issues brushing aside the New York Giants, but that could have been said about last weekend as well.

The Giants are coming off their bye week and have been preparing for this game for two weeks. They will be looking forward to playing in prime time and showing the country that they are a better team than their record reflects. While they will not be making the playoffs this season, they have made significant progress from last year as they continue to build for the future.

The home team are big favorites to get the job done at Raymond James Stadium, with bookmakers listing them to cover 11.5 points. Don’t let that scare you away though – go with the Buccaneers to win big. 

PICKS: Tampa Bay      

ODDS: Tampa Bay (-11.5)
Over/Under: 50

* All odds are via Parx Sportsbook PA.